Research lines in Internal Medicine focus on the development of new protocols and techniques for the diagnostic and prognostic evaluation of liver, gastrointestinal and pulmonary diseases, with an emphasis on identifying biomarkers and potential therapeutic targets.
Liver diseases and their complications
Clinical and translational research of highly relevant liver diseases, with studies of nonalcoholic fatty liver disease (NAFLD), chronic hepatitis, hepatic cirrhosis and hepatocellular carcinoma (HCC). Projects include molecular, genetic, morphological and functional studies, as well as epidemiological and imaging studies, with the main goal being the identification of new diagnosis and prognosis markers, and potential therapeutic targets.
Inflammation and carcinogenesis
Investigation of physiopathological mechanisms and new therapeutic targets in inflammatory diseases and in neoplasia associated with chronic inflammation. Projects focus on disease mechanism and physiological and physiopathological pathways, with
an emphasis on cellular, molecular, genetic, epigenetic, immunological, biochemical, microbiological, structural, morphological and pharmacological studies involving humans.
Imaging Studies applied to Pulmonary Diseases
Evaluation of pulmonary inflammatory response through the use of computer-assisted tomography (CAT), magnetic resonance imaging (MRI) and molecular imaging methods in preclinical models and clinical studies, with the goal of developing new protocols and techniques for the diagnostic study of diseases such as acute lung injury, pulmonary tuberculosis and interstitial pneumonia.
Clerio Azevedo, MD, PhD
Renata Perez, MD, PhD